“Scientists reverse liver cell aging and cut Alzheimer’s-linked protein in half”

Key points

• USC scientists used cinaciguat to treat aging rat livers for two weeks.
• Amyloid beta levels dropped by about 50%, resembling young rats.
• LDL cholesterol levels also returned to youthful levels in treated rats.
• Researchers uncovered a new communication system among liver cells.
• Findings suggest liver-targeted therapy could help reduce Alzheimer’s and atherosclerosis risks.