OriginalSourceNews-medicalLeanUnratedCredibilityUnratedPublished09:33 UTCSourceNews-medicalLeanUnratedCredibilityUnratedPublished09:33 UTC
“RNA-protein interactions reveal new coronavirus drug targets”
Study finds RNA-protein interactions as targets for coronavirus drugs.
Key points
- UCSD and UCR researchers mapped RNA-protein interactions in SARS-CoV-2.
- Identified RNA binding sites for NSP8, NSP12, and N proteins.
- Disrupting these interactions reduced viral replication in cells.
- Findings suggest conserved viral processes could enable broad coronavirus therapies.
- Technique eCLIP enabled genome-wide mapping of RNA-protein contacts.
How it got here
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