concise.
OriginalSourceLive ScienceUnited StatesLeanCenterCredibilityPublished09:00 UTCRatings: AllSides, MBFCSourceLive ScienceUnited StatesLeanCenterCredibilityPublished09:00 UTCRatings: AllSides, MBFC

“'Every time it gets excited — boom — it collapses': How dogs with narcolepsy helped scientists understand the disorder”

Dogs with narcolepsy helped scientists uncover orexin’s role in wakefulness.

Key points

  • Live Science interviews Dr. Emmanuel Mignot, Stanford narcolepsy expert and Lasker Award co-winner.
  • In 1999, orexin was identified as a key factor in wakefulness by two independent teams.
  • Mignot studied narcoleptic dogs, including his own Watson, to explore orexin's function.
  • The Orexin discovery led to new drugs for insomnia and narcolepsy.
  • Stanford's research built on prior work from Dr. Masashi Yanagisawa and clinical observations of narcolepsy.
Read at Live Science

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concise. — Article, Live Science’s original