OriginalSourceScienceDailyUnited StatesLeanCenterCredibilityPublished04:11 UTCRatings: AllSides, MBFCSourceScienceDailyUnited StatesLeanCenterCredibilityPublished04:11 UTCRatings: AllSides, MBFC
“Scientists discover new Alzheimer’s drug that repairs DNA damage and reduces brain inflammation”
Scientists identify KCL-286 as a potential Alzheimer’s therapy that repairs DNA and reduces inflammation.
Key points
- King's College London researchers study KCL-286, originally for spinal cord injuries.
- In mouse models, the drug repaired DNA damage and reduced brain inflammation.
- KCL-286 is orally bioavailable and has completed Phase 1 safety trials.
- The approach targets multiple Alzheimer's processes beyond amyloid-beta and tau.
- Researchers suggest potential for faster clinical testing due to prior human safety data.
How it got here
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