Mpox continues to circulate in the United States and may become endemic.
Mpox cases declined after the 2022 surge but continue circulating in the United States, with thousands recorded in 2024 and 2025.
Key points
From Live Science’s report- Mpox outbreaks surged in 2022, then declined but did not disappear in the US.
- A August report recorded 2,800 cases in 2024 and over 2,500 in 2025.
- Most samples stem from the 2022 outbreak strain, indicating persistence of transmission.
- Experts attribute continued spread to insufficient vaccination and other factors.
- Public health efforts have waned, risking elimination of mpox in the US.
Why it matters. Persistent transmission, limited vaccination, and waning public health efforts may allow mpox to become endemic.
What to watch. Monitor case trends, vaccination coverage, and whether renewed public health measures can reduce or eliminate transmission.
Coverage
Oldest first · UTCCoverage
Oldest first · UTCSourceLive ScienceUnited StatesLeanCenterCredibilityRatings: AllSides, MBFCRead at Live Science“'Mpox has not disappeared': Why the infectious disease is still spreading in the US and may be here to stay”
Why it’s in the Brief
Ranked 10th of 10.
- Starting score
- 5.0
- Public-interest topic
- +1.0
- Public-interest terms in the text
- +1.25
- High-reliability sources
- +0.75
- Score
- 8.0
The ranking is the same for everyone.
Perspective mix. 1 center.RatingsAllSides and Media Bias/Fact CheckLean and credibility are curated from their public ratings.Unknown outlets stay unrated, never guessed.